Babar Azam, who made 32 runs from 28 balls when opening for Pakistan, said the knee injury that forced Shaheen Shad Afridi from the attack proved pivotal to the result.
Afridi started brilliantly when removing English opener Alex Hales in the first over but injured his knee when catching Harry Brook in the 13th over, forcing him to seek treatment.
On returning to the field, he was reintroduced into the attack with England requiring 41 runs from five overs but lasted just one ball before being forced off again.
Pakistan batter Shan Masood, who top-scored for his nation with 38 runs from 28 balls, said it was a disappointing moment for his team.
“That was one of the events (that mattered) but there were a lot of other moments that maybe we could have capitalized on,” he said.
“But yes, at the end of that crucial period when Shaheen (got injured), we could have done with his two overs at the end.”